Thymosin beta 4 (Tβ4) is a 43-amino acid peptide that is a major constituent protein of platelets, macrophages, and polymorphonuclear cells, where it acts as a G-actin binding molecule and regulator of actin polymerization. 2 - 5 These cell types function in trauma response and wound repair, and Tβ4 is among the first genes to be.

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Thymosin beta 4 ophthalmic solution for dry eye: a ...

Thymosin beta 4 ophthalmic solution for dry eye: a randomized, placebo-controlled, Phase II clinical trial conducted using the controlled adverse environment (CAE™) model This study confirms the efficacy of 0.1% Tβ4 as a topical treatment for relief of signs and symptoms of dry eye.

Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution ...

Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution in Patients With Dry Eye The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.

Thymosin Beta 4 (Tβ4) is a synthetic copy of the naturally-occurring 43-amino acid peptide that is found in a variety of tissues. Tβ4 promotes/accelerates wound repair in dermal, ocular, and cardiac animal models.

Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution ...

Thymosin beta 4 ophthalmic solution for dry eye: A randomized, placebo-controlled, phase II clinical trial conducted using the controlled adverse environment (CAE ™) model. Clin Ophthalmol. 2015; 9 :877-884. doi: 10.2147/OPTH.S80954.
The present invention relates to a method for preparing an ophthalmic preparation containing thymosin beta-4. According to the preparation method of the present invention, since an ophthalmic preparation containing thymosin beta-4 is prepared in the presence of an inert gas, contact between thymosin beta-4 and oxygen is blocked, thereby enabling the activity of thymosin beta-4 to be maintained.

Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution ...

thymosin beta 4 (tβ4) is a 43-amino acid peptide that is a major constituent protein of platelets, macrophages, and polymorphonuclear cells, where it acts as a g-actin binding molecule and regulator of actin polymerization. 2 - 5 these cell types function in trauma response and wound repair, and tβ4 is among the first genes to be upregulated in … Thymosin β4 (Tβ4), a small, naturally occurring protein, promotes complete and faster corneal healing than saline alone or prescription agents (doxycycline and cyclosporine) in various animal models of eye injury and in human trials improves both the signs and symptoms of moderate to severe dry eye. 19 View 1 excerpt, cites background

rockville, md., jan. 25, 2022 /prnewswire/ -- regenerx biopharmaceuticals, inc. (otcqb: rgrx) ("regenerx"), a clinical-stage drug development company focused on tissue protection, repair, and.

Thymosin beta 4 ophthalmic solution for dry eye: a ...

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