The entourage effect refers to the synergistic interaction of various compounds present in cannabis, such as cannabinoids, terpenes, and other phytochemicals. According to this concept, the combined effect of these compounds working together is greater than the effect of any single compound in isolation.

In cannabis, the entourage effect suggests that cannabinoids like THC and CBD, along with terpenes, flavonoids, and other plant compounds, work together to produce a more comprehensive and potent effect on the body and mind. This means that the overall therapeutic potential and effects of cannabis are not solely attributed to a single cannabinoid but rather the collective influence of multiple components.

For example, terpenes are aromatic compounds found in cannabis and other plants. They contribute to the distinctive flavors and aromas of different cannabis strains, but they also have their own potential therapeutic properties. Some terpenes, such as myrcene, pinene, and limonene, have been associated with anti-inflammatory, analgesic, and mood-enhancing effects. When combined with cannabinoids, these terpenes may enhance or modulate the effects of cannabinoids and contribute to the overall experience.

The entourage effect has important implications for the development of cannabis-based medicines and products. It suggests that utilizing whole-plant extracts or preserving the natural composition of cannabis may result in more effective and well-rounded therapeutic outcomes compared to isolated compounds. However, further research is still needed to fully understand the mechanisms and extent of the entourage effect and how it can be harnessed for medical and therapeutic purposes.

In order to experience the benefits of the Entourage Effect, it is recommended to consume pure cannabis products (like dried flower) and cannabis products that have been made specifically to preserve a "full spectrum" of cannabinoids, flavonoids and terpenes.