1.The characteristics of autoimmune disease as follow:

A.There are high titer autoantibodies or sensitized lymphocytes can be detected in the patient blood.

B. Autoantibodies or the sensitized lymphocytes interact with target antigens in the tissues and cells, resulting pathological damage and dysfunction in the corresponding tissues and organs.

C. A similar model can be replicated in animal experiments.

D. The disease and autoimmune response intensity is closely related.

E. Most unexplained autoimmune diseases are often recurrent and chronic persistent. F. There is a genetic predisposition.