Elevated levels of serum B12 (cobalamin above about 600 pmol/L) in the absence of dietary supplementation or injections may be a diagnostic sign of serious disease. In sucases B12 is thought to be a marker for disease, not the causal agent. One cause of elevated cobalamin is general liver disease, since hepatic cytolysis releases B12, and the affected liver shows decreased cobalamin clearance. Thus, acute hepatitis, cirrhosis, hepatocellular carcinoma and metastatic liver disease can also be accompanied by an increase in circulating cobalamin.

Heart and blood vessel disease-Vitamin B12, in combination with vitamin B6 and folate (vitamin B9), has been shown to control high levels of homocysteine in the blood. Elevated homocysteine might increase your risk of diseases of the heart and blood vessels (cardiovascular disease). Despite this benefit, there's no evidence to show that vitamin B12 supplements prevent heart disease. Dementia-Vitamin B12 deficiency is associated with dementia and low cognitive function, but it's not clear whether vitamin B12 supplements might help prevent or treat dementia. Athletic performance-Unless you have a vitamin B12 deficiency, there's no evidence that vitamin B12 supplements will boost your energy or make you a better athlete. To know more about the Vitamin B12 ELISA Kit, please visit Creative Diagnostics.