The Mayo Clinic research team has developed a new type of cancer-fighting nanoparticle aimed at shrinking breast cancer tumors while also preventing the recurrence of the disease. They tried a modular design using colloidal nanoparticles as a substrate to construct multiple bispecific nano-biomaterials (mBiNE) to improve selectivity and eliminate cancer cells by immunomodulating. Nano-drugs can interact with immune cells and have the ability to penetrate into the entire immune system, resulting in a potent immune response to the treatment of human disease. This method is based on the existing cancer immunotherapy and will open up a new chapter for the nanomedical immunotherapy.

According to the research, mice that received an injection with nanoparticles showed a 70% to 80% reduction in tumor size , and more surprising result is that mice received nanoparticle injections were resistant to cancer cells, and there was no recurrence of cancer occurred even in a month after exposure to cancer cells. The study is published in Nature Nanotechnology.