Testosterone propionate must be injected every 2-3 days, but testosterone enanthate (doses of 200-250 mg) and testosterone cypionate have longer durations of action and can be injected every 2-3 weeks, for replacement therapy of hypogonadism.
Effects on sexual interest appear after 3 weeks plateauing at 6 weeks, with no further increments expected beyond. Changes in erections/ejaculations may require up to 6 months. Effects on quality of life manifest within 3-4 weeks, but maximum benefits take longer.
Injections of Testosterone will last approximately 15-17 days and after that there will be a dramatic drop. The 14 day treatment schedule keeps that dramatic drop from occurring. How long will it take to see improvements?
Testosterone propionate possesses a relatively short half-life compared with other testosterone esters at approximately 4.5 days.
If you injected 100 mg on at the beginning of the week and another 100 mg towards the end of the week, your peak isn't as high and your low isn't as low. Twice per week is preferred for the balance of testosterone delivery.
How to use Testosterone Cypionate Vial. This medication is given by injection into the buttock muscle as directed by your doctor, usually every 1 to 4 weeks. Do not inject this medication into a vein. Dosage is based on your medical condition, testosterone blood levels, and response to treatment.
After a patient has been on testosterone injections, I measure a trough testosterone on day of injection (before it is given) and a peak testosterone level about 24 to 48 hours after the injection. The goal is to keep the peak from being too high and the trough from being too low.
When you inject testosterone, you're putting a depot of oil into muscle tissue which is slowly dispersed into the bloodstream (for several days, or even weeks, depending on the ester). As a side effect of this, you might experience injection site soreness for a few days after the fact.
Testosterone injections are typically intramuscular - that is, given directly into a muscle. Two relatively easy and accessible sites for intramuscular injection are the deltoid (upper arm) or the glut (upper back portion of the thigh, ie, the butt cheek).
The USA FDA recommended starting dose for male hypogonadism is 50 to 400 mg IM every 2 to 4 weeks (41). The Endocrine Society Clinical Practice Guidelines for testosterone therapy suggest an alternative of either 75 to 100 mg IM weekly or 150 to 200 mg IM every 2 weeks (3).
1 ml per week is 200 mg per week of testosterone. This is a replacement dose not shown to increase lean mass significantly in the short term. However, using higher doses may also increase red blood cell production and blood viscosity, so your doctor needs to monitor your hematocrit blood levels.
Testosterone is a naturally occurring sex hormone that is produced in a man's testicles. Small amounts of testosterone are also produced in a woman's ovaries and adrenal system. Testosterone injection is used in men and boys to treat conditions caused by a lack of this hormone, such as delayed puberty or growth.