Electric field therapy is a non-invasive method of tumor treatment that uses alternating electric fields of specific frequency and intensity to selectively destroy mitosis in cancer cells. Electric field therapy can target proteins that are critical to the cancer cell cycle, leading to mitotic arrest, which can cause apoptosis in cancer cells and activate the patient's own anti-tumor immune response. Electric field therapy has been approved by the FDA for new diagnostic and recurrent gliomas. Experiments with other local solid tumors are ongoing.