Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed to reduce pain, inflammation, and stiffness in AS patients. Medications like indomethacin and naproxen are frequently used for their anti-inflammatory properties. In more severe cases, alternative medications such as golimumab, certolizumab pegol, adalimumab, etanercept, and infliximab may be recommended to address the specific needs of each individual. These medications target the inflammatory response in the body, providing much-needed relief from pain and stiffness.