In addition, CLCs have also been found in eosinophil-mediated inflammation such as chronic sinusitis and parasitic infections, as well as in eosinophil invasive tumors. This indicates the presence of CLCs in the presence of eosinophil-mediated inflammation sites. Clinical studies have found abundant eosinophils in allergic diseases such as asthma and chronic sinusitis. Further testing revealed that the structures of the crystals of Gal10 and CLCs were detected in tissues removed from patients with these diseases. To further validate the experimental results, Gal10 crystals, which are very similar to the CLCs obtained from patients, were synthesized. The researchers injected Gal10 crystals into the airways of mice.