Most outages are an inconvenience to manage calmly. However, some signs mean you should seek help or evacuate rather than continue waiting it out.
If you or someone in your home is feeling seriously unwell and a power outage is part of the picture, don't wait to see if it passes on its own - treat physical symptoms as the priority, not the inconvenience of the outage itself.
When safety is genuinely in question, it is always better to seek help and have it turn out to be unnecessary than to wait too long.